Can you start up a business with loan?

I have never taken any loan in my life and I'm not planning on doing so to start a business. What will happen when the business doesn't become successful? I'll be in debt, no sir, thank you. Keep your loan.
 
I wouldn't want to start a new business already in debt up to my eyeballs. I'd be afraid that I'd never dig myself out of that whole.
 
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