I would buy a nice size property in a wooded area with a modest house and start a farm, then invest the majority of the extra money in stocks, bonds, and p2p lending.
First I'd spend a few hundred on some games I've been meaning to buy, then I'd get the NX at launch, put about half of it in my IRA, and keep the rest in checking and let it accumulate.
I'd make a few wise investments, quadruple my profit, throw several million in a savings account, and live off the interest. Of course I'd also be building myself a nice home, away from civilization. There I could focus on music or any hobbies I'd like to pursue. I don't want to be Bill Gates rich but enough to live comfortably for the rest of my life would be nice.